Title : A multi-kinase inhibitor APG-2449 enhances the antitumor effect of ibrutinib in esophageal squamous cell carcinoma via EGFR/FAK pathway inhibition.

Pub. Date : 2021 Jan

PMID : 33159967






1 Functional Relationships(s)
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1 The combination therapy of APG-2449 and ibrutinib could significantly down-regulate the phosphorylation level of MEK/ERK and AKT. ibrutinib AKT serine/threonine kinase 1 Homo sapiens