Pub. Date : 2020
PMID : 33149616
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin Combined with 4SC-202 Inhibited the Migration and Invasion of OSCC via STAT3/TWIST1. | Metformin | signal transducer and activator of transcription 3 | Homo sapiens |
| 2 | In addition, the phosphorylation level of STAT3 decreased after the administration of metformin or/and 4SC-202. | Metformin | signal transducer and activator of transcription 3 | Homo sapiens |
| 3 | Conclusion: Metformin and 4SC-202 suppressed the invasion and migration of OSCC through inhibition of STAT3/TWIST1, and this scheme can serve as a novel therapeutic strategy for OSCC. | Metformin | signal transducer and activator of transcription 3 | Homo sapiens |