Title : Role of Sevoflurane on Natural Killer Group 2, Member D-Mediated Immune Response in Non-Small-Cell Lung Cancer: An In Vitro Study.

Pub. Date : 2020 Nov 3

PMID : 33139690






3 Functional Relationships(s)
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1 RESULTS At 12.5, 25, 50, and 100 muM, sevoflurane increased the expression of NKG2D ligands (ULBP2-3 and MICA, ULBP1-3, ULBP1-3, and ULBP1, respectively). Sevoflurane killer cell lectin like receptor K1 Homo sapiens
2 Sevoflurane decreased the expression of NKG2D ligands at 200 muM (MICA/B). Sevoflurane killer cell lectin like receptor K1 Homo sapiens
3 CONCLUSIONS Sevoflurane could suppress NKG2D-mediated NK cell cytotoxicity and increased expression of MMPs and migration in NCI-H23 cells. Sevoflurane killer cell lectin like receptor K1 Homo sapiens