Title : Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay.

Pub. Date : 2020 Dec

PMID : 33137690






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 An enzyme-linked immunosorbent assay indicated that, albeit, not as potent as the covalent positive control (GC376), our leads inhibited the Mpro with activity in the micromolar range, and an order of effectiveness of hypericin and cyanidin-3-O-glucoside > SRT2104 > SRT1720. cyanidin-3-o-glucoside NEWENTRY Severe acute respiratory syndrome-related coronavirus