Pub. Date : 2020 Oct
PMID : 33121309
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Downregulation of miR-365 induced expression of NKX homeobox-1 (NKX2-1), epidermal growth factor receptor (EGFR), phosphoinositide-3-kinase (PI3K), and p-Akt proteins in an in vitro model of NSCLC. | mir-365 | NK2 homeobox 1 | Homo sapiens |
| 2 | Inhibition of NKX2-1 reduced the effects of miR-365 on cell growth, metastasis, and invasion of NSCLC. | mir-365 | NK2 homeobox 1 | Homo sapiens |
| 3 | CONCLUSIONS: The study established that the serum miR-365 suppresses NSCLC cell metastasis and invasion in patients with bone metastasis of lung cancer via EGFR/PI3K through NKX2-1. | mir-365 | NK2 homeobox 1 | Homo sapiens |