Title : A compound combination screening approach with potential to identify new treatment options for paediatric acute myeloid leukaemia.

Pub. Date : 2020 Oct 28

PMID : 33116257






1 Functional Relationships(s)
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1 We identified a combination of ABT-737, a Bcl-2 family inhibitor and Purvalanol A, a CDK inhibitor, as a potential targeted therapy for AML patients with an MLL rearrangement and an FLT3-ITD. purvalanol B lysine methyltransferase 2A Homo sapiens