Title : Serine synthesis influences tamoxifen response in ER+ human breast carcinoma.

Pub. Date : 2021 Jan

PMID : 33112838






2 Functional Relationships(s)
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Protein Name
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1 We confirmed that higher PSAT1 and PHGDH expression correlates negatively with poorer outcomes in tamoxifen treated ER+ BC patients. Tamoxifen phosphoglycerate dehydrogenase Homo sapiens
2 Conversely, silencing of either PSAT1 or PHGDH resulted in greater sensitivity to 4-OHT treatment in LCC9 tamoxifen-resistant cells. Tamoxifen phosphoglycerate dehydrogenase Homo sapiens