Pub. Date : 2021 Feb
PMID : 33111210
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 6,4"-dihydroxy-7-methoxyflavanone protects against H2O2-induced cellular senescence by inducing SIRT1 and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Additionally, Akt and ERK were activated with different kinetics after H2O2 exposure, and Akt activity inhibition attenuated SA-beta-gal activity augmentation. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |
3 | We also found that DMF inhibited H2O2-induced Akt phosphorylation. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |