Title : Assessment of structural chromosomal instability phenotypes as biomarkers of carboplatin response in triple negative breast cancer: the TNT trial.

Pub. Date : 2021 Jan

PMID : 33098992






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1 BACKGROUND: In the TNT trial of triple negative breast cancer (NCT00532727), germline BRCA1/2 mutations were present in 28% of carboplatin responders. Carboplatin BRCA1 DNA repair associated Homo sapiens