Title : NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model.

Pub. Date : 2021 Jan

PMID : 33096251






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the presence of ROS, KEAP1 sensor cysteines are directly or indirectly engaged resulting in NRF2 release, nuclear translocation, and activation of its target genes. Cysteine nuclear factor, erythroid derived 2, like 2 Mus musculus