Title : F2R Polymorphisms and Clopidogrel Efficacy and Safety in Patients With Minor Stroke or TIA.

Pub. Date : 2021 Jan 5

PMID : 33093222






5 Functional Relationships(s)
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1 OBJECTIVE: To investigate the association between protease-activated receptor-1 (PAR-1) gene F2R polymorphisms and efficacy of clopidogrel for minor stroke or TIA. Clopidogrel coagulation factor II thrombin receptor Homo sapiens
2 OBJECTIVE: To investigate the association between protease-activated receptor-1 (PAR-1) gene F2R polymorphisms and efficacy of clopidogrel for minor stroke or TIA. Clopidogrel coagulation factor II thrombin receptor Homo sapiens
3 OBJECTIVE: To investigate the association between protease-activated receptor-1 (PAR-1) gene F2R polymorphisms and efficacy of clopidogrel for minor stroke or TIA. Clopidogrel coagulation factor II thrombin receptor Homo sapiens
4 The association between F2R IVSn-14 A/T polymorphism and clopidogrel response was present regardless of the carrier status of the CYP2C19 loss-of-function alleles. Clopidogrel coagulation factor II thrombin receptor Homo sapiens
5 CONCLUSIONS: Among patients with minor ischemic stroke or TIA who were receiving clopidogrel and aspirin, those carrying the F2R IVSn-14 T allele had a lower rate of recurrent stroke than those who were not. Clopidogrel coagulation factor II thrombin receptor Homo sapiens