Title : The GPER1/SPOP axis mediates ubiquitination-dependent degradation of ERĪ± to inhibit the growth of breast cancer induced by oestrogen.

Pub. Date : 2021 Feb 1

PMID : 33069770






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Functionally, GPER1 activation inhibits 17beta-oestradiol (E2)-induced ER + breast cancer cell proliferation, migration, and invasion in vitro and tumour growth in vivo. Estradiol G protein-coupled estrogen receptor 1 Homo sapiens
2 Functionally, GPER1 activation inhibits 17beta-oestradiol (E2)-induced ER + breast cancer cell proliferation, migration, and invasion in vitro and tumour growth in vivo. Estradiol G protein-coupled estrogen receptor 1 Homo sapiens