Title : Effects of CYP2B6 polymorphisms on plasma nevirapine concentrations: a systematic review and meta-analysis.

Pub. Date : 2020 Oct 15

PMID : 33060725






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Effects of CYP2B6 polymorphisms on plasma nevirapine concentrations: a systematic review and meta-analysis. Nevirapine cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 Cytochrome P450 (CYP) is involved in the metabolism of nevirapine (NVP); especially, CYP2B6 has been known to be one of the main enzymes involved in NVP metabolism. Nevirapine cytochrome P450 family 2 subfamily B member 6 Homo sapiens
3 We found that carriers of the CYP2B6 516TT genotype had a 2.18 microg/mL higher NVP concentration than did the GG or GT (95% CI 1.28-3.08). Nevirapine cytochrome P450 family 2 subfamily B member 6 Homo sapiens