Pub. Date : 2020 Dec 25
PMID : 33060204
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The primary substrates of Dnf2 are glucosylceramide (GlcCer) and phosphatidylcholine ((PC) or their lyso-lipid derivatives), and we find that these substrates compete with each other for transport. | Glucosylceramides | aminophospholipid-translocating P4-type ATPase DNF2 | Saccharomyces cerevisiae S288C |
| 2 | The primary substrates of Dnf2 are glucosylceramide (GlcCer) and phosphatidylcholine ((PC) or their lyso-lipid derivatives), and we find that these substrates compete with each other for transport. | Glucosylceramides | aminophospholipid-translocating P4-type ATPase DNF2 | Saccharomyces cerevisiae S288C |
| 3 | Surprisingly, application of lipids that are poor transport substrates differentially affect PC and GlcCer transport by Dnf2, thus altering substrate preference. | Glucosylceramides | aminophospholipid-translocating P4-type ATPase DNF2 | Saccharomyces cerevisiae S288C |