Title : The SWI/SNF ATPase BRG1 stimulates DNA end resection and homologous recombination by reducing nucleosome density at DNA double strand breaks and by promoting the recruitment of the CtIP nuclease.

Pub. Date : 2020 Nov

PMID : 33044911






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Finally, inactivation of BRG1 renders cells sensitive to anti-cancer drugs that induce DSBs. dsbs SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Homo sapiens