Title : Effects of azacitidine in 93 patients with IDH1/2 mutated acute myeloid leukemia/myelodysplastic syndromes: a French retrospective multicenter study.

Pub. Date : 2021 Feb

PMID : 33043739






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) mutations in Myeloid Neoplams (MNs) exhibit DNA hypermethylation via 2-hydroxyglutarate (2HG) over-production. alpha-hydroxyglutarate isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens