Pub. Date : 1987
PMID : 3304205
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Of the family of P-450 cytochromes occurring in rabbit liver microsomes, only isozyme 3a (P-450ALC) is induced by alcohol administration and is effective in catalyzing the reaction: ethanol +02+NADPH+H+----acetaldehyde +2H2O+NADP+. | Alcohols | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Of the family of P-450 cytochromes occurring in rabbit liver microsomes, only isozyme 3a (P-450ALC) is induced by alcohol administration and is effective in catalyzing the reaction: ethanol +02+NADPH+H+----acetaldehyde +2H2O+NADP+. | Alcohols | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | P-450ALC catalyzes the activation of foreign compounds such as acetaminophen, various nitrosamines, and carbon tetrachloride and is therefore believed to play an important role in the enhanced toxicity of these substances accompanying alcohol administration. | Alcohols | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |