Title : Phα1β, a dual blocker of TRPA1 and Cav2.2, as an adjuvant drug in opioid therapy for postoperative pain.

Pub. Date : 2020 Dec

PMID : 33038354






1 Functional Relationships(s)
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1 Preoperative repeated treatment with morphine increased the expression of Cav2 and TRPA1 channels in spinal cord, and caused tolerance and withdrawal syndrome, which were reversed with a single injection of Phalpha1beta (30 pmol/site). Morphine caveolin 2 Mus musculus