Title : Tralopyril induces developmental toxicity in zebrafish embryo (Danio rerio) by disrupting the thyroid system and metabolism.

Pub. Date : 2020 Dec 1

PMID : 33027873






1 Functional Relationships(s)
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1 Tralopyril decreased the thyroid hormone concentrations in embryos and changed the transcriptions of the related genes (TRHR, TSHbeta, TSHR, Nkx2.1, Dio1, TRalpha, TRbeta, TTR and UGT1ab). 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile iodothyronine deiodinase 1 Danio rerio