Title : BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

Pub. Date : 2021 Jan 1

PMID : 33022573






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BPA modulates the WDR5/TET2 complex to regulate ERbeta expression in eutopic endometrium and drives the development of endometriosis. bisphenol A estrogen receptor 1 Homo sapiens
2 This study aimed to explore the effects of bisphenol A (BPA) exposure on EM development from the perspective of the regulation of ERbeta expression in eutopic endometrium via the H3K4me3-related epigenetic pathway. bisphenol A estrogen receptor 1 Homo sapiens
3 This study aimed to explore the effects of bisphenol A (BPA) exposure on EM development from the perspective of the regulation of ERbeta expression in eutopic endometrium via the H3K4me3-related epigenetic pathway. bisphenol A estrogen receptor 1 Homo sapiens
4 In conclusion, our study suggests that BPA exposure promotes EM development by upregulating ERbeta expression in eutopic endometrium via the WDR5/TET2-mediated epigenetic pathway. bisphenol A estrogen receptor 1 Homo sapiens