Pub. Date : 2020
PMID : 33021979
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | co-planar PCB metabolite exposure (Lext H-1: 1.95-3.91) results in activation of AhR (Eralpha/beta)/Nrf2, Rev-Erbbeta, Erralpha, Dio3 (Dio2) and Tralpha limbs with a Delta Cmicro contraction of 0.89 and Delta Cmicro expansion of 1.05 as compared to p-dioxin. | Polychlorinated Biphenyls | iodothyronine deiodinase 2 | Homo sapiens |
2 | co-, ortho-planar PCB metabolite exposure results in activation of Car/PxR, Pparalpha (Srebf1,-Lxrbeta), Arnt (AhR-Erbeta), AR, Dio1 (Dio2) and Trbeta limbs with a Delta Cmicro contraction of 0.73 and Delta Cmicro expansion of 1.18 (as compared to p-dioxin). | Polychlorinated Biphenyls | iodothyronine deiodinase 2 | Homo sapiens |