Title : Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain.

Pub. Date : 2020 Oct

PMID : 33021976






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The disengaged NPC1 adopts a flexed conformation that approaches the lipid bilayer, and could represent a conformational state primed to receive a sterol molecule from the soluble lysosomal cholesterol carrier NPC2. Sterols NPC intracellular cholesterol transporter 2 Homo sapiens