Pub. Date : 2021 Feb
PMID : 33015978
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Altered expression of miR-141 and HDAC6 was introduced to identify their functions in thalidomide-mediated events. | Thalidomide | histone deacetylase 6 | Rattus norvegicus |
| 2 | miR-141 was responsible for thalidomide-mediated protective events by targeting HDAC6. | Thalidomide | histone deacetylase 6 | Rattus norvegicus |
| 3 | Overexpression of HDAC6 blocked the protection of thalidomide against PQ-induced injury via activating the IkBalpha-NF-kappaB signalling pathway. | Thalidomide | histone deacetylase 6 | Rattus norvegicus |
| 4 | Collectively, this study evidenced that thalidomide protects lung tissues from PQ-induced injury through a miR-141/HDAC6/IkBalpha-NF-kappaB axis. | Thalidomide | histone deacetylase 6 | Rattus norvegicus |