Pub. Date : 2020
PMID : 33014113
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin Regulates ERCC1 Expression and Enhances Oxaliplatin Sensitivity in Resistant Colorectal Cancer Cells through Its Effects on miR-409-3p. | Curcumin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
| 2 | Methods: To study the regulation effect of curcumin on ERCC1 expression and its effects on miRNAs, the L-OHP-resistant colorectal cancer cell line HCT116/L-OHP was established. | Curcumin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
| 3 | Curcumin was found to inhibit ERCC1 through its ability to modulate miR-409-3p. | Curcumin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |
| 4 | Conclusion: Curcumin can overcome L-OHP resistance in colorectal cancer cells through its effects on miR-409-3p mediated ERCC1 expression. | Curcumin | ERCC excision repair 1, endonuclease non-catalytic subunit | Homo sapiens |