Title : Lung adenocarcinoma-related TNF-α-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.

Pub. Date : 2020 Sep

PMID : 33000506






2 Functional Relationships(s)
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1 In this study, we explored whether TNF-alpha-mediated inflammation upregulates MHC-II on AT-II cells to trigger Treg expansion in inflammation-driven lung adenocarcinoma (IDLA). treg tumor necrosis factor Homo sapiens
2 Thus, tumor cells of AT-II cellular origin contribute to Treg expansion in an MHC-II-dependent manner in TNF-alpha-mediated IDLA. treg tumor necrosis factor Homo sapiens