Title : Long non‑coding RNA PLK1S1 was associated with renal cell carcinoma progression by interacting with microRNA‑653 and altering C‑X‑C chemokine receptor 5 expression.

Pub. Date : 2020 Nov

PMID : 33000253






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Functional analyses demonstrated that a miR-653 inhibitor promoted short hairpin PLK1S1-attenuated cell proliferation, invasion and sorafenib resistance of RCC cells. Sorafenib kizuna centrosomal protein Homo sapiens
2 In conclusion, the present study revealed that PLK1S1 promoted tumor progression and sorafenib resistance in RCC through regulation of the miR-653/CXCR5 axis, which may offer a novel treatment strategy for patients with RCC. Sorafenib kizuna centrosomal protein Homo sapiens