Title : Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf.

Pub. Date : 2020 Sep 30

PMID : 32999280






1 Functional Relationships(s)
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1 In the screen for bioactive inhibitors of the Otub1/c-Maf axis for MM treatment, nanchangmycin (Nam), a polyketide antibiotic, was identified to suppress c-Maf activity in the presence of Otub1. Polyketides OTU domain, ubiquitin aldehyde binding 1 Mus musculus