Pub. Date : 2020 Sep 23
PMID : 32989221
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High-throughput drug testing with 528 emerging and clinical oncology compounds of OC cell lines and patient-derived cells revealed that dexamethasone treatment increased the sensitivity to several AKT/PI3K targeted kinase inhibitors, while significantly decreasing the efficacy of chemotherapeutics such as taxanes, as well as anti-apoptotic compounds such as SMAC mimetics. | Dexamethasone | AKT serine/threonine kinase 1 | Homo sapiens |