Title : Critical role of IL-33, but not IL-25 or TSLP, in silica crystal-mediated exacerbation of allergic airway eosinophilia.

Pub. Date : 2020 Dec 10

PMID : 32977946






3 Functional Relationships(s)
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1 IL-33, but not IL-25 or TSLP, and type 2 cytokines such as IL-5 and IL-13 were critically involved in silica"s exacerbation of OVA-induced airway eosinophilia in mice. Silicon Dioxide interleukin 13 Mus musculus
2 These observations suggest that IL-33 induced in epithelial cells by silica activates ILCs to produce IL-5 and/or IL-13, contributing to silica"s exacerbation of OVA-induced airway eosinophilia in mice. Silicon Dioxide interleukin 13 Mus musculus
3 These observations suggest that IL-33 induced in epithelial cells by silica activates ILCs to produce IL-5 and/or IL-13, contributing to silica"s exacerbation of OVA-induced airway eosinophilia in mice. Silicon Dioxide interleukin 13 Mus musculus