Title : Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer.

Pub. Date : 2020 Oct 12

PMID : 32976774






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1 Evidence from patient samples in this study suggests that activation of transforming growth factor beta signaling and epithelial-mesenchymal transition by cholesterol-lowering statins may promote the basal type of PDAC, conferring poor outcomes in patients. Cholesterol tumor necrosis factor Homo sapiens