CPRiL

5 Functional Relationships(s) Download
	Sentence	Compound Name	Protein Name	Organism
1	Both ACE2 and heparin can bind independently to spike protein in vitro, and a ternary complex can be generated using heparin as a scaffold.	Heparin	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2
2	Electron micrographs of spike protein suggests that heparin enhances the open conformation of the RBD that binds ACE2.	Heparin	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2
3	Unfractionated heparin, non-anticoagulant heparin, heparin lyases, and lung heparan sulfate potently block spike protein binding and/or infection by pseudotyped virus and authentic SARS-CoV-2 virus.	Heparin	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2
4	Unfractionated heparin, non-anticoagulant heparin, heparin lyases, and lung heparan sulfate potently block spike protein binding and/or infection by pseudotyped virus and authentic SARS-CoV-2 virus.	Heparin	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2
5	Unfractionated heparin, non-anticoagulant heparin, heparin lyases, and lung heparan sulfate potently block spike protein binding and/or infection by pseudotyped virus and authentic SARS-CoV-2 virus.	Heparin	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2