Title : Mediation of hypersensitivity reactions during hemodialysis by IgE antibodies against ethylene oxide.

Pub. Date : 1987 Apr

PMID : 3297007






4 Functional Relationships(s)
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1 Mediation of hypersensitivity reactions during hemodialysis by IgE antibodies against ethylene oxide. Ethylene Oxide immunoglobulin heavy constant epsilon Homo sapiens
2 In seven of nine patients who had experienced a severe hypersensitivity reaction (type II or type III), high titers of IgE antibodies against ETO (greater than 3.0 PRU/mL) were found. Ethylene Oxide immunoglobulin heavy constant epsilon Homo sapiens
3 However, plasma levels of IgE specific for ETO were in the normal range (less than 0.35 PRU/mL) in most (30/37) patients who had experienced a mild (type I) reaction. Ethylene Oxide immunoglobulin heavy constant epsilon Homo sapiens
4 We conclude that ETO causes most severe hypersensitivity reactions by an IgE-mediated mechanism. Ethylene Oxide immunoglobulin heavy constant epsilon Homo sapiens