Title : Modulation of CYP2C9 activity and hydrogen peroxide production by cytochrome b5.

Pub. Date : 2020 Sep 23

PMID : 32968106






1 Functional Relationships(s)
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1 Regarding NADPH-dependent ROS production, soluble recombinant cyt b5 is a potent inhibitor both in HLMs and in CYP2C9 baculosomes, with inhibition constants of 1.04 +- 0.25 and 0.53 +- 0.06 microM cyt b5, respectively. Reactive Oxygen Species 2,4-dienoyl-CoA reductase 1 Homo sapiens