Title : Total Saponins from Paris forrestii Reverse Multidrug Resistance of MCF-7/ADM Cells by Suppression of P-gp via ERK Signaling Pathway.

Pub. Date : 2020 Dec 1

PMID : 32963175






1 Functional Relationships(s)
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1 Moreover, PCT3 significantly increased the accumulation of ADM and Rh123 in MCF-7/ADM cells, suggesting that PCT3 may act by affecting the function of drug efflux pump P-gp, which is encoded by MDR1 gene. Rhodamine 123 phosphoglycolate phosphatase Homo sapiens