Pub. Date : 2020 Dec 1
PMID : 32961495
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cr(VI) induced reactive oxygen species (ROS) overproduction, led to dynamin-related protein 1 (Drp1) translocation to mitochondria and the subsequent mitochondrial fission, contributing to the caspase-3-dependent mitochondrial apoptosis as evidenced by higher mitochondrial permeability transition pore (mPTP) opening rate, lower mitochondrial membrane potential (MMP), and more alanine transaminase (ALT)/aspartate transaminase (AST) leakage into the culture medium. | Chromium | caspase 3 | Homo sapiens |