Title : Therapeutic effect of metformin in the treatment of endometrial cancer.

Pub. Date : 2020 Nov

PMID : 32934724






1 Functional Relationships(s)
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1 The direct mechanisms of metformin include inhibition of the LKB1-AMP-activated protein kinase-mTOR, PI3K-Akt and insulin-like growth factor 1-related signaling pathways, which reduces the proliferation and promotes the apoptosis of EC cells. Metformin serine/threonine kinase 11 Homo sapiens