Title : Metformin attenuates renal interstitial fibrosis through upregulation of Deptor in unilateral ureteral obstruction in rats.

Pub. Date : 2020 Nov

PMID : 32934682






2 Functional Relationships(s)
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1 Metformin attenuates renal interstitial fibrosis through upregulation of Deptor in unilateral ureteral obstruction in rats. Metformin DEP domain containing MTOR-interacting protein Rattus norvegicus
2 In conclusion, the present results suggested that metformin attenuated RIF of UUO rats, and the mechanism of action was found to be associated with the increase in Deptor expression and inhibition of the mTOR/p70S6K pathway in the kidneys of UUO rats. Metformin DEP domain containing MTOR-interacting protein Rattus norvegicus