Title : TET2 directs mammary luminal cell differentiation and endocrine response.

Pub. Date : 2020 Sep 15

PMID : 32934200






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We show that TET2 and FOXP1 form a chromatin complex that mediates demethylation of ESR1, GATA3, and FOXA1, three key genes that are known to coordinately orchestrate mammary luminal lineage specification and endocrine response, and also are often silenced by DNA methylation in aggressive breast cancers. Phenobarbital GATA binding protein 3 Mus musculus