Title : TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.

Pub. Date : 2020 Sep 14

PMID : 32924931






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 TMEM79 interacts with FZD during biogenesis and promotes FZD degradation independent of ZNRF3/RNF43 ubiquitin ligases (R-spondin receptors). fzd transmembrane protein 79 Homo sapiens
2 TMEM79 specifically inhibits USP8 deubiquitination of FZD, thereby governing USP8 substrate specificity and promoting FZD degradation. fzd transmembrane protein 79 Homo sapiens
3 TMEM79 specifically inhibits USP8 deubiquitination of FZD, thereby governing USP8 substrate specificity and promoting FZD degradation. fzd transmembrane protein 79 Homo sapiens