Title : Resveratrol prevents TNF-α-induced VCAM-1 and ICAM-1 upregulation in endothelial progenitor cells via reduction of NF-κB activation.

Pub. Date : 2020 Sep

PMID : 32924701






2 Functional Relationships(s)
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1 RESULTS: MNC adhesion to TNF-alpha-treated EPCs and VCAM-1/ICAM-1/E-selectin levels in EPCs were increased following TNF-alpha stimulation and decreased following RSV treatment. Resveratrol selectin E Homo sapiens
2 RSV"s mechanism of action might involve downregulation of VCAM-1, ICAM-1 and E-selectin by partial blockade of TNF-alpha-induced NF-kappaB activation and IkappaB-alpha phosphorylation in EPCs. Resveratrol selectin E Homo sapiens