Title : Conventional Molecular Dynamics and Metadynamics Simulation Studies of the Binding and Unbinding Mechanism of TTR Stabilizers AG10 and Tafamidis.

Pub. Date : 2020 Oct 7

PMID : 32915538






2 Functional Relationships(s)
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Protein Name
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1 Conventional molecular dynamics and metadynamics simulation studies of the binding and unbinding mechanism of TTR stabilizers AG10 and tafamidis. tyrphostin 8 transthyretin Homo sapiens
2 AG10 stabilizes TTR tetramer by forming H-bonds with S117 to mimic the protective effect of T119M. tyrphostin 8 transthyretin Homo sapiens