Title : Targeting of BCR-ABL1 and IRE1α induces synthetic lethality in Philadelphia-positive acute lymphoblastic leukemia.

Pub. Date : 2021 Feb 25

PMID : 32915195






1 Functional Relationships(s)
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1 BCR-ABL1-positive acute lymphoblastic leukemia (ALL) cell survival is dependent on the inositol requiring enzyme 1 alpha (IRE1alpha) branch of the unfolded protein response. Inositol c-abl oncogene 1, non-receptor tyrosine kinase Mus musculus