Title : Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents.

Pub. Date : 2020 Nov

PMID : 32911194






1 Functional Relationships(s)
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1 In addition, docking studies revealed that the sugar-tail fragment of the target compounds participated in interactions with hydrophilic subpocket at the surface of hCA IX active site and supported the CA IX inhibitory activities of carbohydrate-based sulfonamide derivatives. Sulfonamides carbonic anhydrase 9 Homo sapiens