Pub. Date : 2020 Jun 30
PMID : 32895203
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gefitinib significantly lowered intracellular lactic acid level of the cells (P < 0.05) and down-regulated the expressions of PKM2 and HK2 proteins (P < 0.05) and PI3K-Akt-mTOR signaling pathway-associated proteins (P < 0.05). | Gefitinib | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Gefitinib induces apoptosis of the cells possibly by affecting glycolysis and PI3K-Akt-mTOR signaling pathway. | Gefitinib | AKT serine/threonine kinase 1 | Homo sapiens |