Pub. Date : 2021 Apr
PMID : 32886384
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TCS segments were found only in Fgfr2C342Y/C342Y (100%) and Fgfr2C342Y/+ (72%) tracheas. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |
| 2 | TCS segments were found only in Fgfr2C342Y/C342Y (100%) and Fgfr2C342Y/+ (72%) tracheas. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |
| 3 | Histologic analyses confirmed TCS among the Fgfr2C342Y/C342Y and Fgfr2C342Y/+ groups, without appreciable differences in cartilage morphology, cell size, or density; no histologic differences were observed among other Fgfr2 lines compared to controls. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |
| 4 | Histologic analyses confirmed TCS among the Fgfr2C342Y/C342Y and Fgfr2C342Y/+ groups, without appreciable differences in cartilage morphology, cell size, or density; no histologic differences were observed among other Fgfr2 lines compared to controls. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |
| 5 | Histologic analyses confirmed TCS among the Fgfr2C342Y/C342Y and Fgfr2C342Y/+ groups, without appreciable differences in cartilage morphology, cell size, or density; no histologic differences were observed among other Fgfr2 lines compared to controls. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |
| 6 | CONCLUSION: This study found TCS phenotypes only in the Fgfr2C342Y mouse lines. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |
| 7 | These data support further study of the Fgfr2 mouse lines and the investigation of other Fgfr2 variants to better understand their role in tracheal development and TCS formation. | 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide | fibroblast growth factor receptor 2 | Mus musculus |