Title : The role of WNT/β-catenin signaling pathway and glutamine metabolism in the pathogenesis of CCl4-induced liver fibrosis: Repositioning of niclosamide and concerns about lithium.

Pub. Date : 2020 Dec

PMID : 32882667






1 Functional Relationships(s)
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1 RESULTS: The group of niclosamide-and-CCl4-treated rats showed a significant decrease in total bilirubin, ALT and AST, beta-catenin, l-hydroxyproline, l-glutaminase activity, and gene expression of TGF-beta1 and Dvl2. Niclosamide segment polarity protein dishevelled homolog DVL-2 Rattus norvegicus