Title : Thioredoxin Decreases Anthracycline Cardiotoxicity, But Sensitizes Cancer Cell Apoptosis.

Pub. Date : 2021 Feb

PMID : 32880787






2 Functional Relationships(s)
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1 Here, we present evidence that cancer cells overexpressing Trx undergo enhanced apoptosis in response to daunomycin. Daunorubicin thioredoxin 1 Rattus norvegicus
2 However, rat embryonic cardiomyocytes (H9c2 cells) overexpressing Trx were protected against daunomycin-mediated apoptosis, but H9c2 cells with decreased levels of active Trx showed enhanced apoptosis in response to daunomycin. Daunorubicin thioredoxin 1 Rattus norvegicus