Title : Antiproliferative effect of mitochondria-targeting allobetulin 1,2,3-triazolium salt derivatives and their mechanism of inducing apoptosis of cancer cells.

Pub. Date : 2020 Dec 1

PMID : 32866757






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Compounds 4n and 4q acted on mitochondria to cause an increase in intracellular reactive oxygen species and a change in the level of apoptosis-related protein (Bcl-2, Bcl-xL and Bax), which resulted in a decrease in membrane potential and activation of caspase family to induce cancer cells apoptosis. 4q family with sequence similarity 215 member A Homo sapiens