Title : Multi-site Investigation of Genetic Determinants of Warfarin Dose Variability in Latinos.

Pub. Date : 2021 Jan

PMID : 32860733






1 Functional Relationships(s)
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1 In the U.S. cohort, VKORC1 and CYP2C9 variants were associated with lower warfarin dose (beta=-0.29, p<2.0x10-16 ; beta=-0.21, p=4.7x10-7 , respectively) whereas CYP4F2 and NQO1 variants were associated with higher dose (beta=0.10, p=2x10-4 ; beta=0.10, p=0.01, respectively). Warfarin NAD(P)H quinone dehydrogenase 1 Homo sapiens