Title : IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas.

Pub. Date : 2020 Aug 26

PMID : 32843616






1 Functional Relationships(s)
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1 Conversely, inhibition of MEK1/2 by MEK1/2 inhibitor (U0126) or knockdown of MEK1 and MEK2 by corresponding mek1 and mek2 siRNA enhanced AKT phosphorylation, indicating mutual inhibition between AKT and MEK. U 0126 AKT serine/threonine kinase 1 Homo sapiens